COPI buds 60-nm lipid droplets from reconstituted water–phospholipid–triacylglyceride interfaces, suggesting a tension clamp function

Intracellular trafficking between organelles is achieved by coat protein complexes, coat protomers, that bud vesicles from bilayer membranes. Lipid droplets are protected by a monolayer and thus seem unsuitable targets for coatomers. Unexpectedly, coat protein complex I (COPI) is required for lipid...

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Detalhes bibliográficos
Main Authors: Thiam, Abdou Rachid, Antonny, Bruno, Wang, Jing, Delacotte, Jérôme, Wilfling, Florian, Walther, Tobias C., Beck, Rainer, Rothman, James E., Pincet, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Physical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746913/
https://ncbi.nlm.nih.gov/pubmed/23901109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307685110
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