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Homozygous nonsense mutation Trp28X in the LHB gene causes male hypogonadism

PURPOSE: The purpose of this study was to investigate a novel mutation in the luteinizing hormone beta-subunit (LHB) gene in one male patient with hypogonadism due to selective luteinizing hormone (LH) deficiency. METHODS: Sanger sequencing of one 28-year-old man born to consanguineous parents was p...

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Detalles Bibliográficos
Publicado en:J Assist Reprod Genet
Main Authors: Yang, Xiaoyu, Ochin, H., Shu, Li, Liu, Jinyong, Shen, Jiandong, Liu, Jiayin, Lin, Changsong, Cui, Yugui
Formato: Artigo
Idioma:Inglês
Publicado: Springer US 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984881/
https://ncbi.nlm.nih.gov/pubmed/29476300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-018-1133-5
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