Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway

BACKGROUND: It is essential to understand the mechanisms responsible for hepatocellular carcinoma (HCC) progression and chemoresistance in order to identify prognostic biomarkers as well as potential therapeutic avenues. Recent findings have shown that SLIT3 appears to function as a novel tumor supp...

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Pubblicato in:BMC Cancer
Autori principali: Ng, Lui, Chow, Ariel K. M., Man, Johnny H. W., Yau, Thomas C. C., Wan, Timothy M. H., Iyer, Deepak N., Kwan, Virginia H. T., Poon, Ronnie T. P., Pang, Roberta W. C., Law, Wai-Lun
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984734/
https://ncbi.nlm.nih.gov/pubmed/29859044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4326-5
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