Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway

BACKGROUND: It is essential to understand the mechanisms responsible for hepatocellular carcinoma (HCC) progression and chemoresistance in order to identify prognostic biomarkers as well as potential therapeutic avenues. Recent findings have shown that SLIT3 appears to function as a novel tumor supp...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Ng, Lui, Chow, Ariel K. M., Man, Johnny H. W., Yau, Thomas C. C., Wan, Timothy M. H., Iyer, Deepak N., Kwan, Virginia H. T., Poon, Ronnie T. P., Pang, Roberta W. C., Law, Wai-Lun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984734/
https://ncbi.nlm.nih.gov/pubmed/29859044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4326-5
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