Suppression of Slit3 induces tumor proliferation and chemoresistance in hepatocellular carcinoma through activation of GSK3β/β-catenin pathway

BACKGROUND: It is essential to understand the mechanisms responsible for hepatocellular carcinoma (HCC) progression and chemoresistance in order to identify prognostic biomarkers as well as potential therapeutic avenues. Recent findings have shown that SLIT3 appears to function as a novel tumor supp...

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Vydáno v:BMC Cancer
Hlavní autoři: Ng, Lui, Chow, Ariel K. M., Man, Johnny H. W., Yau, Thomas C. C., Wan, Timothy M. H., Iyer, Deepak N., Kwan, Virginia H. T., Poon, Ronnie T. P., Pang, Roberta W. C., Law, Wai-Lun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984734/
https://ncbi.nlm.nih.gov/pubmed/29859044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4326-5
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