Cholesterol Esterification Inhibition Suppresses Prostate Cancer Metastasis by Impairing the Wnt/β-catenin Pathway

Dysregulation of cholesterol is a common characteristic of human cancers including prostate cancer. This study observed an aberrant accumulation of cholesteryl ester in metastatic lesions using Raman spectroscopic analysis of lipid droplets in human prostate cancer patient tissues. Inhibition of cho...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cancer Res
Prif Awduron: Lee, Hyeon Jeong, Li, Jie, Vickman, Renee E, Li, Junjie, Liu, Rui, Durkes, Abigail C, Elzey, Bennett D, Yue, Shuhua, Liu, Xiaoqi, Ratliff, Timothy L, Cheng, Ji-Xin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984676/
https://ncbi.nlm.nih.gov/pubmed/29545473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0665
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