Cholesterol Esterification Inhibition Suppresses Prostate Cancer Metastasis by Impairing the Wnt/β-catenin Pathway

Dysregulation of cholesterol is a common characteristic of human cancers including prostate cancer. This study observed an aberrant accumulation of cholesteryl ester in metastatic lesions using Raman spectroscopic analysis of lipid droplets in human prostate cancer patient tissues. Inhibition of cho...

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Vydáno v:Mol Cancer Res
Hlavní autoři: Lee, Hyeon Jeong, Li, Jie, Vickman, Renee E, Li, Junjie, Liu, Rui, Durkes, Abigail C, Elzey, Bennett D, Yue, Shuhua, Liu, Xiaoqi, Ratliff, Timothy L, Cheng, Ji-Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984676/
https://ncbi.nlm.nih.gov/pubmed/29545473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0665
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