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Augmented Th17 Differentiation Leads to Cutaneous and Synovio-Entheseal Inflammation in a Novel Model of Psoriatic Arthritis
OBJECTIVE: To introduce a novel pre-clinical animal model of psoriatic arthritis, R26STAT3C(stopfl/fl) CD4Cre mice, and investigate the role of Th17 cytokines in the disease pathogenesis. METHODS: We characterized a novel murine model of Th17-driven cutaneous and synovio-entheseal disease directed b...
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| Publicado no: | Arthritis Rheumatol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5984671/ https://ncbi.nlm.nih.gov/pubmed/29439292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40447 |
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