Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter

Ten-eleven translocation (Tet) family-mediated DNA oxidation represents an epigenetic modification capable of converting 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), which regulates various biological processes. However, it is unknown whether Tet family affects mesenchymal stem cells...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Yang, Ruili, Yu, Tingting, Kou, Xiaoxing, Gao, Xiang, Chen, Chider, Liu, Dawei, Zhou, Yanheng, Shi, Songtao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984622/
https://ncbi.nlm.nih.gov/pubmed/29858571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04464-6
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