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Proteome-Wide Evaluation of Two Common Protein Quantification Methods

Proteomics experiments commonly aim to estimate and detect differential abundance across all expressed proteins. Within this experimental design, some of the most challenging measurements are small fold changes for lower abundance proteins. While bottom-up proteomics methods are approaching comprehe...

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Pubblicato in:J Proteome Res
Autori principali: O’Connell, Jeremy D., Paulo, Joao A., O’Brien, Jonathon J., Gygi, Steven P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984592/
https://ncbi.nlm.nih.gov/pubmed/29635916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00016
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