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Characterization of tumor heterogeneity by latent haplotypes: a sequential Monte Carlo approach

Tumor samples obtained from a single cancer patient spatially or temporally often consist of varying cell populations, each harboring distinct mutations that uniquely characterize its genome. Thus, in any given samples of a tumor having more than two haplotypes, defined as a scaffold of single nucle...

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Veröffentlicht in:PeerJ
Hauptverfasser: Ogundijo, Oyetunji E., Wang, Xiaodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984585/
https://ncbi.nlm.nih.gov/pubmed/29868266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4838
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