Temperature regulates NF-κB dynamics and function through timing of A20 transcription

NF-κB signaling plays a pivotal role in control of the inflammatory response. We investigated how the dynamics and function of NF-κB were affected by temperature within the mammalian physiological range (34 °C to 40 °C). An increase in temperature led to an increase in NF-κB nuclear/cytoplasmic osci...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Harper, C. V., Woodcock, D. J., Lam, C., Garcia-Albornoz, M., Adamson, A., Ashall, L., Rowe, W., Downton, P., Schmidt, L., West, S., Spiller, D. G., Rand, D. A., White, M. R. H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984538/
https://ncbi.nlm.nih.gov/pubmed/29760065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1803609115
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