A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage

The gut epithelium acts to separate host immune cells from unrestricted interactions with the microbiota and other environmental stimuli. In response to epithelial damage or dysfunction, immune cells are activated to produce interleukin (IL)-22, which is involved in repair and protection of barrier...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Ngo, Vu L., Abo, Hirohito, Maxim, Estera, Harusato, Akihito, Geem, Duke, Medina-Contreras, Oscar, Merlin, Didier, Gewirtz, Andrew T., Nusrat, Asma, Denning, Timothy L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
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PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984499/
https://ncbi.nlm.nih.gov/pubmed/29760082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718902115
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