Ythdf2-mediated m(6)A mRNA clearance modulates neural development in mice

BACKGROUND: N(6)-methyladenosine (m(6)A) modification in mRNAs was recently shown to be dynamically regulated, indicating a pivotal role in multiple developmental processes. Most recently, it was shown that the Mettl3-Mettl14 writer complex of this mark is required for the temporal control of cortic...

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Vydáno v:Genome Biol
Hlavní autoři: Li, Miaomiao, Zhao, Xu, Wang, Wei, Shi, Hailing, Pan, Qingfei, Lu, Zhike, Perez, Sonia Peña, Suganthan, Rajikala, He, Chuan, Bjørås, Magnar, Klungland, Arne
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984442/
https://ncbi.nlm.nih.gov/pubmed/29855337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1436-y
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