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Enantioselective Halolactonization Reactions using BINOL-derived Bifunctional Catalysts: Methodology, Diversification, and Applications

A general protocol is described for inducing enantioselective halolactonizations of unsaturated carboxylic acids using novel bifunctional organic catalysts derived from a chiral binaphthalene scaffold. Bromo- and iodolactonization reactions of diversely substituted, unsaturated carboxylic acids proc...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Klosowski, Daniel W., Hethcox, J. Caleb, Paull, Daniel H., Fang, Chao, Donald, James R., Shugrue, Christopher R., Pansick, Andrew D., Martin, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984189/
https://ncbi.nlm.nih.gov/pubmed/29717607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.8b00490
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