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The Bromodomain Inhibitor JQ1 Enhances the Responses to All-trans Retinoic Acid in HL-60 and MV4-11 Leukemia Cells

All-trans retinoic acid (ATRA) is a highly effective treatment for acute promyelocytic leukemia (APL), a cytogenetically distinct subtype of acute myeloid leukemia (AML). However, ATRA-based treatment is not effective in other subtypes of AML. In non-APL AML, ATRA signaling pathway is impaired or do...

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Detalhes bibliográficos
Publicado no:Int J Stem Cells
Main Authors: Kang, Changhee, Kim, C-Yoon, Kim, Hyuk Soon, Park, Se-Pill, Chung, Hyung-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Stem Cell Research 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984067/
https://ncbi.nlm.nih.gov/pubmed/29699387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15283/ijsc18021
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