Diazoxide inhibits of ER stress-mediated apoptosis during oxygen-glucose deprivation in vitro and cerebral ischemia-reperfusion in vivo

Neuroprotective strategies using diazoxide (DZX) have been demonstrated to limit ischemia/reperfusion (I/R)-induced injury and cell apoptosis. In type 2 diabetes mellitus, DZX has been reported to improve β-cell function and reduce their apoptosis, through suppressing endoplasmic reticulum (ER) stre...

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發表在:Mol Med Rep
Main Authors: Lei, Xiaofeng, Lei, Lijian, Zhang, Zhiqing, Cheng, Yan
格式: Artigo
語言:Inglês
出版: D.A. Spandidos 2018
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983977/
https://ncbi.nlm.nih.gov/pubmed/29693708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8925
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