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Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models

Pyrrolizidine alkaloids (PAs) are a widespread class of hepatotoxic heterocyclic organic compounds found in approximately 3% of world flora. Some PAs have been shown to have genotoxic and carcinogenic effects. The present study focuses on the toxicity effects of four dry extracts obtained from medic...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Seremet, Oana Cristina, Olaru, Octavian Tudorel, Gutu, Claudia Maria, Nitulescu, George Mihai, Ilie, Mihaela, Negres, Simona, Zbarcea, Cristina Elena, Purdel, Carmen Nicoleta, Spandidos, Demetrios A., Tsatsakis, Aristides M., Coleman, Michael D., Margina, Denisa Marilena
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983973/
https://ncbi.nlm.nih.gov/pubmed/29620235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8795
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