Lambertianic Acid Sensitizes Non-Small Cell Lung Cancers to TRAIL-Induced Apoptosis via Inhibition of XIAP/NF-κB and Activation of Caspases and Death Receptor 4

Lambertianic acid (LA) is a biologically active compound from the leaves of Pinus koraiensis. In the present study, apoptotic mechanisms of LA plus TNF-related apoptosis-inducing ligand (TRAIL) were elucidated in non-small cell lung cancer cells (NSCLCs). Cytotoxicity assay, flow cytometry, immunopr...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Ahn, Deok Soo, Lee, Hyo Jung, Hwang, Jisung, Han, Hyukgyu, Kim, Bonglee, Shim, BumSang, Kim, Sung-Hoon
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983579/
https://ncbi.nlm.nih.gov/pubmed/29772677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19051476
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