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Impaired reward prediction error encoding and striatal-midbrain connectivity in depression

Anhedonia (hyposensitivity to rewards) and negative bias (hypersensitivity to punishments) are core features of major depressive disorder (MDD), which could stem from abnormal reinforcement learning. Emerging evidence highlights blunted reward learning and reward prediction error (RPE) signaling in...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Kumar, Poornima, Goer, Franziska, Murray, Laura, Dillon, Daniel G., Beltzer, Miranda L., Cohen, Andrew L., Brooks, Nancy H., Pizzagalli, Diego A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983542/
https://ncbi.nlm.nih.gov/pubmed/29540863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0032-x
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