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Impaired reward prediction error encoding and striatal-midbrain connectivity in depression

Anhedonia (hyposensitivity to rewards) and negative bias (hypersensitivity to punishments) are core features of major depressive disorder (MDD), which could stem from abnormal reinforcement learning. Emerging evidence highlights blunted reward learning and reward prediction error (RPE) signaling in...

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Bibliografske podrobnosti
izdano v:Neuropsychopharmacology
Main Authors: Kumar, Poornima, Goer, Franziska, Murray, Laura, Dillon, Daniel G., Beltzer, Miranda L., Cohen, Andrew L., Brooks, Nancy H., Pizzagalli, Diego A.
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983542/
https://ncbi.nlm.nih.gov/pubmed/29540863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0032-x
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