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The desA and desB genes from Clostridium scindens ATCC 35704 encode steroid-17,20-desmolase
Clostridium scindens is a gut microbe capable of removing the side-chain of cortisol, forming 11β-hydroxyandrostenedione. A cortisol-inducible operon (desABCD) was previously identified in C. scindens ATCC 35704 by RNA-Seq. The desC gene was shown to encode a cortisol 20α-hydroxysteroid dehydrogena...
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| Udgivet i: | J Lipid Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Biochemistry and Molecular Biology
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5983398/ https://ncbi.nlm.nih.gov/pubmed/29572237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M083949 |
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