Adolescent Nicotine Exposure Alters GABA(A) Receptor Signaling in the Ventral Tegmental Area and Increases Adult Ethanol Self-Administration

Adolescent smoking is associated with pathological drinking later in life, but the biological basis for this vulnerability is unknown. To examine how adolescent nicotine exposure influences subsequent ethanol intake, nicotine was administered during adolescence or adulthood, and responses to alcohol...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Thomas, Alyse M., Ostroumov, Alexey, Kimmey, Blake A., Taormina, Madison B., Holden, William M., Kim, Kristen, Brown-Mangum, Tiffany, Dani, John A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983379/
https://ncbi.nlm.nih.gov/pubmed/29617674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.03.030
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