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Tauroursodeoxycholic acid binds to the G-protein site on light activated rhodopsin

The heterotrimeric G-protein binding site on G-protein coupled receptors remains relatively unexplored regarding its potential as a new target of therapeutic intervention or as a secondary site of action by the existing drugs. Tauroursodeoxycholic acid bears structural resemblance to several compoun...

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Détails bibliographiques
Publié dans:Exp Eye Res
Auteurs principaux: Lobysheva, E., Taylor, C.M., Marshall, G.R., Kisselev, O.G.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983371/
https://ncbi.nlm.nih.gov/pubmed/29454859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2018.02.015
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