Single-cell RNA-seq reveals a subpopulation of prostate cancer cells with enhanced cell cycle-related transcription and attenuated androgen response

Increasing evidence suggests the presence of minor cell subpopulations in prostate cancer that are androgen independent and poised for selection as dominant clones after androgen-deprivation therapy. In this study, we investigated this phenomenon by stratifying cell subpopulations based on transcrip...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Horning, Aaron M., Wang, Yao, Lin, Che-Kuang, Louie, Anna D., Jadhav, Rohit R., Hung, Chia-Nung, Wang, Chiou-Miin, Lin, Chun-Lin, Kirma, Nameer B., Liss, Michael A., Kumar, Addanki P., Sun, LuZhe, Liu, Zhijie, Chao, Wei-Ting, Wang, Qianben, Jin, Victor X., Chen, Chun-Liang, Huang, Tim H.-M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983359/
https://ncbi.nlm.nih.gov/pubmed/29233929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1924
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