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Blocking IFNAR1 inhibits multiple myeloma–driven Treg expansion and immunosuppression

Despite significant advances in the treatment of multiple myeloma (MM), most patients succumb to disease progression. One of the major immunosuppressive mechanisms that is believed to play a role in myeloma progression is the expansion of regulatory T cells (Tregs). In this study, we demonstrate tha...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Kawano, Yawara, Zavidij, Oksana, Park, Jihye, Moschetta, Michele, Kokubun, Katsutoshi, Mouhieddine, Tarek H., Manier, Salomon, Mishima, Yuji, Murakami, Naoka, Bustoros, Mark, Pistofidis, Romanos Sklavenitis, Reidy, Mairead, Shen, Yu J., Rahmat, Mahshid, Lukyanchykov, Pavlo, Karreci, Esilida Sula, Tsukamoto, Shokichi, Shi, Jiantao, Takagi, Satoshi, Huynh, Daisy, Sacco, Antonio, Tai, Yu-Tzu, Chesi, Marta, Bergsagel, P. Leif, Roccaro, Aldo M., Azzi, Jamil, Ghobrial, Irene M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983341/
https://ncbi.nlm.nih.gov/pubmed/29558366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88169
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