FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis

While the transcription factor forkhead box M1 (FOXM1) is well known as a proto-oncogene, its potential role in lung fibroblast activation has never been explored. Here, we show that FOXM1 is more highly expressed in fibrotic than in normal lung fibroblasts in humans and mice. FOXM1 was required not...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Clin Invest
Главные авторы: Penke, Loka R., Speth, Jennifer M., Dommeti, Vijaya L., White, Eric S., Bergin, Ingrid L., Peters-Golden, Marc
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983327/
https://ncbi.nlm.nih.gov/pubmed/29733296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87631
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы