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DEPDC5 takes a second hit in familial focal epilepsy

Loss-of-function mutations in a single allele of the gene encoding DEP domain–containing 5 protein (DEPDC5) are commonly linked to familial focal epilepsy with variable foci; however, a subset of patients presents with focal cortical dysplasia that is proposed to result from a second-hit somatic mut...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Autor principal: Anderson, Matthew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983308/
https://ncbi.nlm.nih.gov/pubmed/29708509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121052
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