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The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E‐transformed cells
Metabolic reprogramming, as exemplified by the shift from oxidative phosphorylation to glycolysis, is a common feature of transformed cells. In many tumors, altered metabolism is also reflected in increased reactive oxygen species (ROS) levels, which contribute to proliferation and survival signalin...
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| Publicado no: | Mol Oncol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5983121/ https://ncbi.nlm.nih.gov/pubmed/29624862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12199 |
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