Relationship between KCNQ1 (LQT1) and KCNH2 (LQT2) gene mutations and sudden death during illegal drug use

Long QT syndrome (LQTS), a congenital genetic disorder, can cause torsades de pointes (TdP), and lethal cardiac arrhythmia may result from ingestion of cardiotoxic drugs. Methamphetamine (MP) and new psychoactive substances (NPSs) can trigger TdP due to QT prolongation, leading to sudden death. We t...

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Publicado en:Sci Rep
Main Authors: Nagasawa, Sayaka, Saitoh, Hisako, Kasahara, Shiori, Chiba, Fumiko, Torimitsu, Suguru, Abe, Hiroko, Yajima, Daisuke, Iwase, Hirotaro
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981596/
https://ncbi.nlm.nih.gov/pubmed/29855564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26723-8
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