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Relationship between KCNQ1 (LQT1) and KCNH2 (LQT2) gene mutations and sudden death during illegal drug use

Long QT syndrome (LQTS), a congenital genetic disorder, can cause torsades de pointes (TdP), and lethal cardiac arrhythmia may result from ingestion of cardiotoxic drugs. Methamphetamine (MP) and new psychoactive substances (NPSs) can trigger TdP due to QT prolongation, leading to sudden death. We t...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Nagasawa, Sayaka, Saitoh, Hisako, Kasahara, Shiori, Chiba, Fumiko, Torimitsu, Suguru, Abe, Hiroko, Yajima, Daisuke, Iwase, Hirotaro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981596/
https://ncbi.nlm.nih.gov/pubmed/29855564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26723-8
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