Relationship between KCNQ1 (LQT1) and KCNH2 (LQT2) gene mutations and sudden death during illegal drug use

Long QT syndrome (LQTS), a congenital genetic disorder, can cause torsades de pointes (TdP), and lethal cardiac arrhythmia may result from ingestion of cardiotoxic drugs. Methamphetamine (MP) and new psychoactive substances (NPSs) can trigger TdP due to QT prolongation, leading to sudden death. We t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Nagasawa, Sayaka, Saitoh, Hisako, Kasahara, Shiori, Chiba, Fumiko, Torimitsu, Suguru, Abe, Hiroko, Yajima, Daisuke, Iwase, Hirotaro
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981596/
https://ncbi.nlm.nih.gov/pubmed/29855564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26723-8
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