A novel oral camptothecin analog, gimatecan, exhibits superior antitumor efficacy than irinotecan toward esophageal squamous cell carcinoma in vitro and in vivo

Esophageal squamous cell carcinoma (ESCC) is a frequently diagnosed and deadly malignancy with few standard therapeutic options. Camptothecins are considered one of the most promising antitumor drugs. A modified lipophilic analog, gimatecan, was synthesized as a novel oral camptothecin and showed im...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zou, Jianling, Li, Shuang, Chen, Zuhua, Lu, Zhihao, Gao, Jing, Zou, Jianyin, Lin, Xiaoting, Li, Yanyan, Zhang, Cheng, Shen, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981453/
https://ncbi.nlm.nih.gov/pubmed/29855512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0700-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados