HIV LTR-Driven Antisense RNA by Itself Has Regulatory Function and May Curtail Virus Reactivation From Latency

Latently infected T lymphocytes are an important barrier toward eliminating a persistent HIV infection. Here we describe an HIV-based recombinant fluorescent-lentivirus referred to as “rfl-HIV” that enables to analyze sense and antisense transcription by means of fluorescence reporter genes. This mo...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Kobayashi-Ishihara, Mie, Terahara, Kazutaka, Martinez, Javier P., Yamagishi, Makoto, Iwabuchi, Ryutaro, Brander, Christian, Ato, Manabu, Watanabe, Toshiki, Meyerhans, Andreas, Tsunetsugu-Yokota, Yasuko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980963/
https://ncbi.nlm.nih.gov/pubmed/29887842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01066
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