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Perspectives on Non-BLT Humanized Mouse Models for Studying HIV Pathogenesis and Therapy

A variety of humanized mice, which are reconstituted only with human hematopoietic stem cells (HSC) or with fetal thymus and HSCs, have been developed and widely utilized as in vivo animal models of HIV-1 infection. The models represent some aspects of HIV-mediated pathogenesis in humans and are use...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Terahara, Kazutaka, Iwabuchi, Ryutaro, Tsunetsugu-Yokota, Yasuko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8145733/
https://ncbi.nlm.nih.gov/pubmed/33924786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13050776
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