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Detection of Cytochrome P450 Polymorphisms in Breast Cancer Patients May Impact on Tamoxifen Therapy
BACKGROUND: Breast cancer is the most common cancer among women worldwide. Tamoxifen (TAM), a selective estrogen receptor modulator, is widely used in its treatment. TAM is metabolized by cytochrome P450 (CYP450) enzymes, including CYP2D6, CYP3A5 and CYP2C19, whose genetic variations may have clinic...
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| Udgivet i: | Asian Pac J Cancer Prev |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
West Asia Organization for Cancer Prevention
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5980918/ https://ncbi.nlm.nih.gov/pubmed/29479969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2018.19.2.343 |
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