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Separation of plasma‐derived exosomes into CD3((+)) and CD3((–)) fractions allows for association of immune cell and tumour cell markers with disease activity in HNSCC patients

Head and neck squamous cell carcinoma (HNSCC) is a highly immunosuppressive malignancy. Exosomes in HNSCC patients' plasma are enriched in inhibitory cargo and mediate immunosuppression. As these exosomes are products of various cells, the cellular origin of immunoregulatory proteins they carry...

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Библиографические подробности
Опубликовано в: :Clin Exp Immunol
Главные авторы: Theodoraki, M.‐N., Hoffmann, T. K., Whiteside, T. L.
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980445/
https://ncbi.nlm.nih.gov/pubmed/29431869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13113
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