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Spontaneous T-cell responses against the immune check point programmed-death-ligand 1 (PD-L1) in patients with chronic myeloproliferative neoplasms correlate with disease stage and clinical response

The Chronic Myeloproliferative Neoplasms (MPN) are cancers characterized by hyperinflammation and immune deregulation. Concurrently, the expression of the immune check point programmed death ligand 1 (PD-L1) is induced by inflammation. In this study we report on the occurrence of spontaneous T cell...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Holmström, Morten Orebo, Riley, Caroline Hasselbalch, Skov, Vibe, Svane, Inge Marie, Hasselbalch, Hans Carl, Andersen, Mads Hald
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980374/
https://ncbi.nlm.nih.gov/pubmed/29872567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1433521
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