Spontaneous T-cell responses against the immune check point programmed-death-ligand 1 (PD-L1) in patients with chronic myeloproliferative neoplasms correlate with disease stage and clinical response

The Chronic Myeloproliferative Neoplasms (MPN) are cancers characterized by hyperinflammation and immune deregulation. Concurrently, the expression of the immune check point programmed death ligand 1 (PD-L1) is induced by inflammation. In this study we report on the occurrence of spontaneous T cell...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Holmström, Morten Orebo, Riley, Caroline Hasselbalch, Skov, Vibe, Svane, Inge Marie, Hasselbalch, Hans Carl, Andersen, Mads Hald
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
Subjects:
Brief Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980374/
https://ncbi.nlm.nih.gov/pubmed/29872567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1433521
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