The induced RNA‐binding protein, HuR, targets 3′‐UTR region of IL‐6 mRNA and enhances its stabilization in periodontitis

RNA‐binding proteins (RBPs) regulate mRNA stability by binding to the 3′‐untranslated region (UTR) region of mRNA. Human antigen‐R (HuR), one of the RBPs, is involved in the progression of diseases, such as rheumatoid arthritis, diabetes mellitus and some inflammatory diseases. Interleukin (IL)‐6 is...

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Bibliographic Details
Published in:Clin Exp Immunol
Main Authors: Ouhara, K., Munenaga, S., Kajiya, M., Takeda, K., Matsuda, S., Sato, Y., Hamamoto, Y., Iwata, T., Yamasaki, S., Akutagawa, K., Mizuno, N., Fujita, T., Sugiyama, E., Kurihara, H.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980314/
https://ncbi.nlm.nih.gov/pubmed/29393507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.13110
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