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Activity of novel lipid glycine transporter inhibitors on synaptic signalling in the dorsal horn of the spinal cord

BACKGROUND AND PURPOSE: Inhibitory neurotransmission plays an important role in controlling excitability within nociceptive circuits of the spinal cord dorsal horn. Loss of inhibitory signalling is thought to contribute to the development of pathological pain. Preclinical studies suggest that increa...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Winters, Bryony L, Rawling, Tristan, Vandenberg, Robert J, Christie, Macdonald J, Bhola, Rebecca F, Imlach, Wendy L
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980266/
https://ncbi.nlm.nih.gov/pubmed/29500820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14189
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