Activity of novel lipid glycine transporter inhibitors on synaptic signalling in the dorsal horn of the spinal cord

BACKGROUND AND PURPOSE: Inhibitory neurotransmission plays an important role in controlling excitability within nociceptive circuits of the spinal cord dorsal horn. Loss of inhibitory signalling is thought to contribute to the development of pathological pain. Preclinical studies suggest that increa...

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Udgivet i:Br J Pharmacol
Main Authors: Winters, Bryony L, Rawling, Tristan, Vandenberg, Robert J, Christie, Macdonald J, Bhola, Rebecca F, Imlach, Wendy L
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Themed Section: Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980266/
https://ncbi.nlm.nih.gov/pubmed/29500820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14189
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