Novel NADPH oxidase inhibitor VAS2870 suppresses TGF-β-dependent epithelial-to-mesenchymal transition in retinal pigment epithelial cells

NADPH oxidases (NOXs) are important in the pathophysiology of fibrotic diseases. The expression and activity of NOXs are regulated by growth factors, including transforming growth factor (TGF-β). The proliferation of retinal pigment epithelial (RPE) cells following epithelial- to-mesenchymal transit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Med
Prif Awduron: Yang, Jing, Li, Jing, Wang, Qun, Xing, Yao, Tan, Zizhu, Kang, Qianyan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2018
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979836/
https://ncbi.nlm.nih.gov/pubmed/29620174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3612
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