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Novel NADPH oxidase inhibitor VAS2870 suppresses TGF-β-dependent epithelial-to-mesenchymal transition in retinal pigment epithelial cells

NADPH oxidases (NOXs) are important in the pathophysiology of fibrotic diseases. The expression and activity of NOXs are regulated by growth factors, including transforming growth factor (TGF-β). The proliferation of retinal pigment epithelial (RPE) cells following epithelial- to-mesenchymal transit...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: Yang, Jing, Li, Jing, Wang, Qun, Xing, Yao, Tan, Zizhu, Kang, Qianyan
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979836/
https://ncbi.nlm.nih.gov/pubmed/29620174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3612
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