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Automated Exploration of Free Energy Landscapes Based on Umbrella Integration

We present a new approach for automated exploration of free energy landscapes on the basis of the umbrella integration (UI) method. The method to search points in the landscape relies on the normal distributions and gradients of the potential of mean force (PMF) obtained from UI calculations. We app...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Mitsuta, Yuki, Kawakami, Takashi, Okumura, Mitsutaka, Yamanaka, Shusuke
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979611/
https://ncbi.nlm.nih.gov/pubmed/29561821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19040937
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