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Exploring the free-energy landscape of GPCR activation

G-protein–coupled receptors (GPCRs) are a large group of membrane-bound receptor proteins that are involved in a plethora of diverse processes (e.g., vision, hormone response). In mammals, and particularly in humans, GPCRs are involved in many signal transduction pathways and, as such, are heavily s...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Alhadeff, Raphael, Vorobyov, Igor, Yoon, Han Wool, Warshel, Arieh
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187162/
https://ncbi.nlm.nih.gov/pubmed/30257944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1810316115
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