Evaluation of Two Liver Treatment Strategies in a Mouse Model of Niemann–Pick-Disease Type C1

Niemann–Pick-disease type C1 (NPC1) is an autosomal-recessive cholesterol-storage disorder. Besides other symptoms, NPC1 patients develop liver dysfunction and hepatosplenomegaly. The mechanisms of hepatomegaly and alterations of lipid metabolism-related genes in NPC1 disease are still poorly unders...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Ebner, Lynn, Gläser, Anne, Bräuer, Anja, Witt, Martin, Wree, Andreas, Rolfs, Arndt, Frank, Marcus, Vollmar, Brigitte, Kuhla, Angela
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979582/
https://ncbi.nlm.nih.gov/pubmed/29587349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19040972
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