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Increased Regenerative Capacity of the Olfactory Epithelium in Niemann–Pick Disease Type C1

Niemann–Pick disease type C1 (NPC1) is a fatal neurovisceral lysosomal lipid storage disorder. The mutation of the NPC1 protein affects the homeostasis and transport of cholesterol and glycosphingolipids from late endosomes/lysosomes to the endoplasmic reticulum resulting in progressive neurodegener...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Meyer, Anja, Wree, Andreas, Günther, René, Holzmann, Carsten, Schmitt, Oliver, Rolfs, Arndt, Witt, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5412361/
https://ncbi.nlm.nih.gov/pubmed/28383485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18040777
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