Pharmacologic Treatment Assigned for Niemann Pick Type C1 Disease Partly Changes Behavioral Traits in Wild-Type Mice

Niemann-Pick Type C1 (NPC1) is an autosomal recessive inherited disorder characterized by accumulation of cholesterol and glycosphingolipids. Previously, we demonstrated that BALB/c-npc1(nih)Npc1(−/−) mice treated with miglustat, cyclodextrin and allopregnanolone generally performed better than untr...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Schlegel, Victoria, Thieme, Markus, Holzmann, Carsten, Witt, Martin, Grittner, Ulrike, Rolfs, Arndt, Wree, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133866/
https://ncbi.nlm.nih.gov/pubmed/27834854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17111866
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