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Protective Effects of Gomisin N against Hepatic Cannabinoid Type 1 Receptor-Induced Insulin Resistance and Gluconeogenesis

Activation of the hepatic cannabinoid type 1 receptor (CB1R) induces insulin resistance and gluconeogenesis via endoplasmic reticulum (ER) stress, thereby contributing to hyperglycemia. Gomisin N (GN) is a phytochemical derived from Schisandra chinensis. In the current study, we investigated the inh...

詳細記述

保存先:
書誌詳細
出版年:Int J Mol Sci
主要な著者: Nagappan, Arulkumar, Jung, Dae Young, Kim, Ji-Hyun, Jung, Myeong Ho
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979504/
https://ncbi.nlm.nih.gov/pubmed/29570673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19040968
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