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PON-tstab: Protein Variant Stability Predictor. Importance of Training Data Quality

Several methods have been developed to predict effects of amino acid substitutions on protein stability. Benchmark datasets are essential for method training and testing and have numerous requirements including that the data is representative for the investigated phenomenon. Available machine learni...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Yang, Yang, Urolagin, Siddhaling, Niroula, Abhishek, Ding, Xuesong, Shen, Bairong, Vihinen, Mauno
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979465/
https://ncbi.nlm.nih.gov/pubmed/29597263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041009
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