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PON-mt-tRNA: a multifactorial probability-based method for classification of mitochondrial tRNA variations

Transfer RNAs (tRNAs) are essential for encoding the transcribed genetic information from DNA into proteins. Variations in the human tRNAs are involved in diverse clinical phenotypes. Interestingly, all pathogenic variations in tRNAs are located in mitochondrial tRNAs (mt-tRNAs). Therefore, it is cr...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Niroula, Abhishek, Vihinen, Mauno
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4797295/
https://ncbi.nlm.nih.gov/pubmed/26843426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw046
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