A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome

The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol biosynthesis. Adult Wistar rats were divided into five experimental groups: one control group, two Th9 compression (40 g/15 min) groups, and two Th...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Bimbova, Katarina, Bacova, Maria, Kisucka, Alexandra, Pavel, Jaroslav, Galik, Jan, Zavacky, Peter, Marsala, Martin, Stropkovska, Andrea, Fedorova, Jana, Papcunova, Stefania, Jachova, Jana, Lukacova, Nadezda
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979414/
https://ncbi.nlm.nih.gov/pubmed/29642434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041106
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