A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome

The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol biosynthesis. Adult Wistar rats were divided into five experimental groups: one control group, two Th9 compression (40 g/15 min) groups, and two Th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Bimbova, Katarina, Bacova, Maria, Kisucka, Alexandra, Pavel, Jaroslav, Galik, Jan, Zavacky, Peter, Marsala, Martin, Stropkovska, Andrea, Fedorova, Jana, Papcunova, Stefania, Jachova, Jana, Lukacova, Nadezda
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979414/
https://ncbi.nlm.nih.gov/pubmed/29642434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041106
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