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Preclinical Evaluation of Vemurafenib as Therapy for BRAF(V600E) Mutated Sarcomas
The BRAF(V600E) mutation, which in melanoma is targetable with vemurafenib, is also found in sarcomas and we here evaluate the therapeutic potential in sarcoma cell lines. Methods: Four sarcoma cell lines harboring the BRAF(V600E) mutation, representing liposarcomas (SA-4 and SW872), Ewing sarcoma (...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5979358/ https://ncbi.nlm.nih.gov/pubmed/29570692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19040969 |
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