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Microbiota-Derived Uremic Retention Solutes: Perpetrators of Altered Nonrenal Drug Clearance in Kidney Disease

INTRODUCTION: Scientific interest in the gut microbiota is increasing due to improved understanding of its implications in human health and disease. In patients with kidney disease, gut microbiota-derived uremic toxins directly contribute to altered nonrenal drug clearance. Microbial imbalances, kno...

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Detalhes bibliográficos
Publicado no:Expert Rev Clin Pharmacol
Main Authors: Prokopienko, Alexander J., Nolin, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979269/
https://ncbi.nlm.nih.gov/pubmed/28905671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17512433.2018.1378095
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