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Clinical review: Drug metabolism and nonrenal clearance in acute kidney injury

Decreased renal drug clearance is an obvious consequence of acute kidney injury (AKI). However, there is growing evidence to suggest that nonrenal drug clearance is also affected. Data derived from human and animal studies suggest that hepatic drug metabolism and transporter function are components...

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Hlavní autoři: Vilay, A Mary, Churchwell, Mariann D, Mueller, Bruce A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646335/
https://ncbi.nlm.nih.gov/pubmed/19040780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc7093
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